Born and Raised in Spartanburg, SC, Dr. Marcello has been practicing General Dentistry in the Upstate since 1999. He graduated from Wofford College in 1994 with a Bachelor of Science degree in Biology, and went on to the Medical University of South Carolina, where he earned his Doctorate of Medical Dentistry. After graduating from MUSC, he began his residency in Dayton, Ohio at the Dayton VA Medical Hospital. In his spare time, Dr. Marcello enjoys traveling with his family. His wife, Samantha, is the Office Manager here at Dental Innovations. His daughter, Thea, also helps with greeting patients when she comes to work with mommy!

At Dental Innovations LLC, Dr. Marcello provides preventative, restorative, and aesthetic dental care for patients of all ages. We are very proud to provide our patients with the highest quality dental care in Greenville, SC and surrounding areas. We work hard to educate our patients about their treatment options and other oral health issues.


We will gladly accept/bill any type of dental insurance.

Here are some of the many dental insurance carriers that we are currently in network with:


  • Blue Cross Blue Shield of SC 

  • Liberty Dental (WellCare)

  • United Healthcare

  • United Concordia

  • Delta Dental

  • Careington

  • Dentemax

  • Guardian

  • Ameritas

  • Principal

  • MetLife

  • Aetna

  • Cigna

  • And more! Call now for additional details.




Years of Experience

Smiling  Clients

Master Certifications

Happy Staff


Shannon Harris, RDH

Registered Dental Hygienist

Ryan Marcello, DMD 


Jackie Nogueras, CDA

Certified Dental Assistant



Dr. Marcello is professional and works quickly, yet efficiently. As someone who has anxiety about dental work, I appreciate that he doesn't waste any time. The staff has also worked with me, going above and beyond, to get the care I need in a timely manner.

Love the atmosphere and Dr. Marcello and his wonderful staff!!!!! Everyone here really does treat you like FAMILY!!!!! They don't try to rush you in and out. Everyone here takes the time that you need and explain everything and inform you of what is going on!!!!! This means a lot to me.... Thank you Dr. Marcello and your wonderful staff!!!

Dr. Marcello is a gentle caring dentist. My new crown is awesome. If you are looking for a family friendly atmosphere and excellent dental care, I absolutely recommend Dr. Marcello and his team.



Our Address

27 Creekview Court

Greenville, SC 29615

Email: Dentalinnovations@innovateyoursmile.com

 Tel: 864-640-8987

Fax: 855-852-3884

Hours of Operation

Monday – Thursday  8:30AM – 4:30PM

(By Appointment Only. Please call to schedule an appointment before arriving in person.)



© 2023 by We Smile. Proudly created with Wix.com